Past & Current Experiences

Past & Current Experiences

PK/ADA/NAb

  • PD-1 antibody (Opdivo)
    • (Keytruda)
  • PD-L1 antibody (Tecentriq)
  • CTLA-4 antibody (lpilimumab)
  • CTLA-4 fusion protein (Abatacept)
    • (Belatacept)
  • TNF-α fusion protein (Enbrel)
  • TNF-α antibody (Infliximab)
    • (Adalimumab)
  • VEGF fusion protein (Conbercept)
    • (Aflibercept)
  • VEGF antibody (Bevacizumab)
  • Lucentis
  • VEGFR2 antibody (Ramucirumab)
  • EGFR antibody (Cetuximab)
  • CD20 antibody (Rituximab)
  • Her2 antibody (Trastuzumab)
    • (Pertuzumab)
  • Car-T
  • RANKL (Denosumab)
  • IL-6 antibody
  • Insulin analogue
  • Aspart
  • Lispro
  • Glargine
  • Degludec
  • Lispro 50 mixture
  • GLP-1 analogue
  • Exendin-4-HAS fusion protein
  • TPO/romiplostim
  • RANKL antibody
  • PCSK9 antibody
  • Acid α-Glucosidase (GAA)
  • α-Galactosidase A (Gal-A)
  • Factor VIII
  • IL-1β
  • IL-2
  • IL-17A antibody
  • IL-23 antibody
  • FSH
  • GH
  • MCF antibody
  • EPO
  • KGF
  • SOST antibody
  • IgE antibody
  • CD40 antibody
  • FXI antibody

Validated / Qualified Biomarkers

Inflammatory / Immunological disease:

  • BMP-9
  • C-MET
  • HGF
  • IL-8
  • M-CSF
  • MCP-1
  • PARC
  • SDF-1
  • TIMP-1
  • VEGF

Metabolic diseases:

  • Adiponectin, Total
  • GLP-1, Active
  • GLP-1, Total
  • GIP
  • Leptin
  • PYY

Liver injury:

  • Adiponectin, Total
  • αGST
  • CICP
  • TGFb 1
  • TIMP-1

Tumor:

  • BMP9
  • C-MET
  • VEGF
  • HGF
  • IL8
  • M30
  • M65
  • GDF-15
  • CRKL
  • Pro-GRP
  • P53
  • NSE
  • CYFRA21
  • cIAP*
  • xIPA*
  • MDM2*
  • BCL-2/BIM complex*
  • MCL-1/BIM complex*
  • 30-plex chemokine/inflammatory/pro-inflammatory)

* In PBMC cell lysate, others are in biological fluid

Pulmonary disease:

  • Adiponectin, Total
  • IL-6
  • KL-6
  • PARC
  • Tenascin C
  • TGFb 1

Cardiovascular disease:

  • IL-6
  • MCP-1

Osteogenesis:

  • CICP
  • Cartilage disease and Arthritis:
  • PIIINP
  • YKL-40

Endocrine function:

  • Estradiol
  • IGF-1
  • TGFb 1

Renal injury:

  • Cystatin C
  • NGAL